Formulated with 250 mg ibuprofen that targets pain at the source and 500 mg acetaminophen that blocks pain signals in each dose, these coated pills provide relief from a wide variety of aches and pains. Provides headache, toothache, menstrual cramp, muscle pain and lower back pain relief while also relieving minor aches and pains associated with arthritis. The combination of ibuprofen and acetaminophen allows you to take a lower maximum daily dose of each pain medication and still have powerful, eight hour relief.